CLARINEX® Information
CLARINEX® is an antihistamine
— a type of medicine that blocks the action of histamine, a natural
substance in your body that is released by your immune system during an
allergic reaction. Antihistamines are often used to help relieve the symptoms
of seasonal and year-round allergies — itchy, watery eyes; sneezing;
and runny nose — caused by exposure to indoor allergens such as dust
mite, mold spores, pet dander, and outdoor allergens caused by pollen from
trees, grasses, or weeds.
CLARINEX® is also approved to
treat the ongoing itching and rash due to hives from unknown
causes.
CLARINEX® can be safely used
to treat seasonal allergies in adults who at the same time suffer from
mild-to-moderate asthma. CLARINEX® is not
approved for the treatment of asthma. Patients with asthma should speak to
their doctors about an appropriate treatment for asthma.
Studies have shown that grapefruit juice can affect the
absorption of some medications, resulting in changes in the drug concentration
in the bloodstream. In a clinical study of
CLARINEX® administered with grapefruit
juice, there was no effect on the active drug concentration.
CLARINEX® is the first
antihistamine to state in its labeling that grapefruit juice does not affect
the absorption of the active ingredient.
CLARINEX® is available by
prescription only. And unlike many over-the-counter and some prescription
antihistamines, CLARINEX® is nondrowsy when
taken at the recommended doses.
In clinical studies for seasonal and year-round allergies, the
most common side effects with CLARINEX®
(desloratadine) Tablets 5 mg were similar to sugar pill, including sore throat,
dry mouth and fatigue.
In clinical studies for ongoing itching and rash from hives of
unknown cause, the most common side effects with
CLARINEX® (desloratadine) Tablets 5 mg were
headache, nausea, and fatigue.
For more information about
CLARINEX®, ask your doctor or other
healthcare provider.
CLARINEX®, a prescription medication, treats year-round allergy symptoms and ongoing hives of unknown cause, in adults and children 6 months and older, and seasonal allergy symptoms in patients 2 years and older. CLARINEX® 5 mg Tablets and 5 mg RediTabs® Tablets are approved for patients 12 years and older; CLARINEX® 2.5 mg RediTabs® Tablets are approved for patients 6 to 11 years; CLARINEX® Syrup is approved for patients 6 months and older.
Twice-daily CLARINEX-D® 12 HOUR Extended Release Tablets and once-daily CLARINEX-D® 24 HOUR Extended Release Tablets treat the symptoms of seasonal allergies, including nasal congestion, in patients 12 years and older.
IMPORTANT SAFETY INFORMATION
CLARINEX® Tablets side effects in patients 12 years and older were similar to placebo and included sore throat, dry mouth, and fatigue for seasonal and year-round allergy patients, and headache, nausea, and fatigue for patients with ongoing hives of unknown cause.
CLARINEX® Syrup side effects in children 6 to 11 years were similar to placebo. For children 6 months to 5 years, syrup side effects varied by age and included fever, diarrhea, upper respiratory infection, irritability, and coughing.
Due to their pseudoephedrine component, CLARINEX-D® 12 HOUR Extended Release Tablets and CLARINEX-D® 24 HOUR Extended Release Tablets should not be taken by patients with narrow-angle glaucoma (abnormally high eye pressure), difficulty urinating, severe high blood pressure, or severe heart disease, or by patients who have taken a monoamine oxidase (MAO) inhibitor within the past fourteen (14) days. Patients with high blood pressure; diabetes; heart disease; increased intraocular pressure (eye pressure); thyroid, liver or kidney problems; or enlarged prostate should check with their healthcare provider before taking CLARINEX-D® 12 HOUR Extended Release Tablets or CLARINEX-D® 24 HOUR Extended Release Tablets.
Care should be used if CLARINEX-D® 12 HOUR Extended Release Tablets or CLARINEX-D® 24 HOUR Extended Release Tablets are taken with other antihistamines or decongestants because combined effects on the cardiovascular system may be harmful. The most commonly reported adverse events for CLARINEX-D® 12 HOUR Extended Release Tablets were insomnia, headache, dry mouth, fatigue, drowsiness, sore throat, and dizziness. The most commonly reported adverse events for CLARINEX-D® 24 HOUR Extended Release Tablets were dry mouth, headache, insomnia, fatigue, sore throat, and drowsiness.
Click here for important CLARINEX® Tablets/Syrup/RediTabs® Product Information.
Click here for important CLARINEX-D® 12 HOUR Product Information.
Click here for important CLARINEX-D® 24 HOUR Product Information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Note: The information on this site is not intended to be a substitute for professional medical advice. If you have any questions about your treatment or medical condition, please consult your doctor or other qualified health care provider. This site is intended for use by U.S. residents.
