Question and Answer

What are allergies?
How do allergies work?
What is pollen?
Why are some allergies seasonal and others year-round?
Who gets allergies?


Q: What are allergies?

A: The simplest way to think of allergies is this: Your body thinks it has breathed in something dangerous. It mistakes an allergen such as pollen from weeds, grass, or trees for an invader. It's trying to expel them from your body, literally trying to push them out. That's why your nose runs, eyes get watery, you sneeze, cough, and drain.

Yet respiratory allergens such as pollen from grass, trees, or weeds are not dangerous. They're a normal part of our world. So we don't grow up making a habit of avoiding them. That's what makes allergies difficult to treat.

Return to top

Q: How do allergies work?

A: When you breathe in something like pollen, some of it works its way into the lining of your nose, where it encounters your immune system. The first time this happens, your immune system decides the pollen is dangerous, and forms a small amount of antibody to it. That's all that happens. No sneezing, no runny nose, no symptoms.

But the second time you breath in the pollen, and every time thereafter, something different happens. Your immune system remembers the pollen and forms lots of antibody. The antibody stimulated cells located in your nose, eyes, throat, and lungs, named mast cells or basophils, to release a substance called histamine. Histamine, in turn, makes your tissues secrete fluids and become irritated. The result is a runny nose, nasal congestion, sneezing, watery eyes, and itching of the nose, ears, and throat. Your body is trying to expel the pollen you breathed in.

Return to top

Q: What is pollen?

A: Pollen is the male fertilizing agent of plants. To the naked eye, it looks like a fine grain or a particle of dust. For plants to reproduce, they must transfer it from one plant to another. They rely on the wind to sweep pollen into the air and onto female reproductive structures of other plants, a process known as pollination. Unfortunately, we breathe the same pollen-filled air. The pollens that commonly create allergies come from three groups of plants: trees, including common varieties like oak and birch; grasses; and the biggest culprit, ragweed, which causes nearly 75% of all allergies.

Return to top

Q: Why are some allergies seasonal and others year-round?

A: If you have allergies that change with the seasons, they're probably caused by pollen, because different plants pollinate at different times of the year.

Trees release pollen in the spring. Grasses do so in late spring and early summer. Ragweed pollinates in the late summer until the first frost of fall. The exact timing for these three allergy seasons depends on where you live.

Since your allergy symptoms change with the amount of pollen in the air, you'll have more difficulty on windy days, since more pollen is swept into the air. Rain, on the other hand, tends to clear the air. You'll find these times more comfortable.

The full medical term for allergies caused by pollen is seasonal allergic rhinitis; "seasonal" refers to changing with the seasons; rhinitis comes from the ancient Greek word for the nose. But the most common name for these allergies is hay fever. As you've learned, hay has nothing to do with these allergies, and allergies don't cause fevers. The expression comes from the English doctor, Dr. John Bostock, who coined it in 1828. He suffered from severe summer allergies and found it interesting that his problem occurred during the British haying season.

If you have allergies that bother you year-round, they most likely stem from things that don't change with the seasons. The most common include household dust mites, animal dander from pets, feathers, and mold spores. We call these perennial allergens. More often than not, people are allergic to more than one thing. So you may find your symptoms changing more than once each year. For example, you may have difficulty with pollens, but get no relief in the winter due to dust. Or you may have no problem in cold weather, but suffer during the eight months pollination occurs. No two people are exactly the same.

Return to top

Q: Who gets allergies?

A: Like many problems of the immune system, we don't know, as yet, how people develop allergies. We do know that approximately 50 million Americans suffer from allergy symptoms; and that their sensitivity often starts in childhood or young adulthood. We also know that the tendency to develop allergies is inherited.

Return to top

CLARINEX®, a prescription medication, treats year-round allergy symptoms and ongoing hives of unknown cause, in adults and children 6 months and older, and seasonal allergy symptoms in patients 2 years and older. CLARINEX® 5 mg Tablets and 5 mg RediTabs® Tablets are approved for patients 12 years and older; CLARINEX® 2.5 mg RediTabs® Tablets are approved for patients 6 to 11 years; CLARINEX® Syrup is approved for patients 6 months and older.

Twice-daily CLARINEX-D® 12 HOUR Extended Release Tablets and once-daily CLARINEX-D® 24 HOUR Extended Release Tablets treat the symptoms of seasonal allergies, including nasal congestion, in patients 12 years and older.

IMPORTANT SAFETY INFORMATION
CLARINEX® Tablets side effects in patients 12 years and older were similar to placebo and included sore throat, dry mouth, and fatigue for seasonal and year-round allergy patients, and headache, nausea, and fatigue for patients with ongoing hives of unknown cause.

CLARINEX® Syrup side effects in children 6 to 11 years were similar to placebo. For children 6 months to 5 years, syrup side effects varied by age and included fever, diarrhea, upper respiratory infection, irritability, and coughing.

Due to their pseudoephedrine component, CLARINEX-D® 12 HOUR Extended Release Tablets and CLARINEX-D® 24 HOUR Extended Release Tablets should not be taken by patients with narrow-angle glaucoma (abnormally high eye pressure), difficulty urinating, severe high blood pressure, or severe heart disease, or by patients who have taken a monoamine oxidase (MAO) inhibitor within the past fourteen (14) days. Patients with high blood pressure; diabetes; heart disease; increased intraocular pressure (eye pressure); thyroid, liver or kidney problems; or enlarged prostate should check with their healthcare provider before taking CLARINEX-D® 12 HOUR Extended Release Tablets or CLARINEX-D® 24 HOUR Extended Release Tablets.

Care should be used if CLARINEX-D® 12 HOUR Extended Release Tablets or CLARINEX-D® 24 HOUR Extended Release Tablets are taken with other antihistamines or decongestants because combined effects on the cardiovascular system may be harmful. The most commonly reported adverse events for CLARINEX-D® 12 HOUR Extended Release Tablets were insomnia, headache, dry mouth, fatigue, drowsiness, sore throat, and dizziness. The most commonly reported adverse events for CLARINEX-D® 24 HOUR Extended Release Tablets were dry mouth, headache, insomnia, fatigue, sore throat, and drowsiness.

Click here for important CLARINEX® Tablets/Syrup/RediTabs® Product Information.
Click here for important CLARINEX-D® 12 HOUR Product Information.
Click here for important CLARINEX-D® 24 HOUR Product Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Note: The information on this site is not intended to be a substitute for professional medical advice. If you have any questions about your treatment or medical condition, please consult your doctor or other qualified health care provider. This site is intended for use by U.S. residents.

TRUSTe Certified Privacy