Causes and Treatment of Hives

Recurring attacks of hives may be caused by physical agents such as: sunlight, cold, pressure and sweat. Hives caused by such agents is called "physical urticaria". People with this type of hives usually recognize the irritants that cause attacks.

Chronic Urticaria

This is urticaria occurring almost daily and lasting more than six weeks. In the majority of people, no cause or significant aggravating factors can be found. Physical urticaria may be present as well in some patients. Food allergy is seldom a cause of chronic persistent urticaria even though some foods may aggravate it.

Treatment of Urticaria

The best treatment for urticaria is to identify and avoid the cause and any aggravating factors. While investigating the cause, antihistamines can provide symptomatic relief.

Antihistamines are the first line treatment for hives. To avoid side-effects like drowsiness, non-sedative antihistamines are available. Antihistamine creams are probably not effective.

CLARINEX® is approved to treat the itching and rash due to hives from unknown causes. In clinical studies for ongoing itching and rash from hives of unknown cause, the most common side effects with CLARINEX® (desloratadine) Tablets 5 mg were headache, nausea, and fatigue.

CLARINEX®, a prescription medication, treats year-round allergy symptoms and ongoing hives of unknown cause, in adults and children 6 months and older, and seasonal allergy symptoms in patients 2 years and older. CLARINEX® 5 mg Tablets and 5 mg RediTabs® Tablets are approved for patients 12 years and older; CLARINEX® 2.5 mg RediTabs® Tablets are approved for patients 6 to 11 years; CLARINEX® Syrup is approved for patients 6 months and older.

Twice-daily CLARINEX-D® 12 HOUR Extended Release Tablets and once-daily CLARINEX-D® 24 HOUR Extended Release Tablets treat the symptoms of seasonal allergies, including nasal congestion, in patients 12 years and older.

IMPORTANT SAFETY INFORMATION
CLARINEX® Tablets side effects in patients 12 years and older were similar to placebo and included sore throat, dry mouth, and fatigue for seasonal and year-round allergy patients, and headache, nausea, and fatigue for patients with ongoing hives of unknown cause.

CLARINEX® Syrup side effects in children 6 to 11 years were similar to placebo. For children 6 months to 5 years, syrup side effects varied by age and included fever, diarrhea, upper respiratory infection, irritability, and coughing.

Due to their pseudoephedrine component, CLARINEX-D® 12 HOUR Extended Release Tablets and CLARINEX-D® 24 HOUR Extended Release Tablets should not be taken by patients with narrow-angle glaucoma (abnormally high eye pressure), difficulty urinating, severe high blood pressure, or severe heart disease, or by patients who have taken a monoamine oxidase (MAO) inhibitor within the past fourteen (14) days. Patients with high blood pressure; diabetes; heart disease; increased intraocular pressure (eye pressure); thyroid, liver or kidney problems; or enlarged prostate should check with their healthcare provider before taking CLARINEX-D® 12 HOUR Extended Release Tablets or CLARINEX-D® 24 HOUR Extended Release Tablets.

Care should be used if CLARINEX-D® 12 HOUR Extended Release Tablets or CLARINEX-D® 24 HOUR Extended Release Tablets are taken with other antihistamines or decongestants because combined effects on the cardiovascular system may be harmful. The most commonly reported adverse events for CLARINEX-D® 12 HOUR Extended Release Tablets were insomnia, headache, dry mouth, fatigue, drowsiness, sore throat, and dizziness. The most commonly reported adverse events for CLARINEX-D® 24 HOUR Extended Release Tablets were dry mouth, headache, insomnia, fatigue, sore throat, and drowsiness.

Click here for important CLARINEX® Tablets/Syrup/RediTabs® Product Information.
Click here for important CLARINEX-D® 12 HOUR Product Information.
Click here for important CLARINEX-D® 24 HOUR Product Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Note: The information on this site is not intended to be a substitute for professional medical advice. If you have any questions about your treatment or medical condition, please consult your doctor or other qualified health care provider. This site is intended for use by U.S. residents.

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